Interesting cases from Department

Case-1: Aggressive extranodal peripheral T-cell non-Hodgkin's lymphoma


Incisional biopsy specimen along with extracted 46, 47 and 48 teeth

Photomicrograph showing sheets of lymphoid cells (H&E stain , 40x)

Photomicrograph showing IHC positivity for CD45 with intense nuclear brown staining for cell membrane surface (IHC stain, 40x)

Photomicrograph showing small cell T-lymphocytes positive for CD3 with intense nuclear brown staining for cell membrane surface (IHC stain, 40x)

Case No-2: Oncocytic Pleomorphic Adenoma


Gross specimen measuring about 2x2 cm which is grayish white in colour

H&E 10X: Showing ductal formation with eosinophilic coagulum

H&E 100X: Showing oncocytic cells with eosinophilic granular coagulum

PAS 100X: Showing oncocytic cells with granular cytoplasm

Heidenhain's 100X: Showing grey black granules in the

Phosphotungstic acid hematoxylin (PTAH) 40X: Showing blue black granules in the cytoplasm of oncocytes

Transmission Electron Microscopic pictures showing bizarre enlarged oncocytic cells

Case-3: Hyalinizing clear cell carcinoma


Gross Specimen showing mixed tissue (teeth and soft tissue) which is grayish white in colour

Histopathological examination of the specimen from the lesion of the patient in the case report revealing hyalinized areas in the connective tissue with clear cells

Immunohistochemical testing for P63 showing positive reactivity of the clear cells (10×)

Immunohistochemical testing for Pancytokeratin showing positive reactivity of the clear cells (10×)

Case-4: Pyogenic Granuloma


Longitudinal cut section of gross specimen showing grayish white areas

Gross specimen under stereomicroscope (8x) with grayish white areas

H&E section showing areas of calcification, Necrosis and inflammatory infiltrate in pyogenic granuloma

Case-5: Dental Fluorosis


Scanning Electron microscopic pictures of flourapatite crystals in enamel

Case-6: Actinomycosis


Anaerobic culture showing actinomyces colonies of varying size

Case-7: Cytological Smear


H&E stained cytological smear showing cellular atypia